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Macrocyclic Chemistry

Services & Solutions

Services & Solutions

News & Events


Small Molecule

Small Molecule

WuXi TIDES(Oligonucleotide and Peptide CRDMO Service)




Macrocyclic Chemistry

Carbohydrate Chemistry


Macrocyclic Chemistry

Boron Chemistry

Steroids Chemistry


Computer-aided Drug Design


Compound Management

Reaction Condition Screening

Fluorescent Bio-probe and Labeling

Quantum Mechanics

Late Stage Functionalization

Catalysis Screening

Custom Synthesis

Discovery Process Chemistry


Impurity Proofing

Isotopic Labeling Chemistry

Crystallization Platform

Analysis & Purification

Fluorine Chemistry

PROTAC <sup>®</sup> Platform

Flow Chemistry Service


Photoredox Chemistry

Macrocyclic Compounds Platform

Capability of Macrocyclic Compound Platform

Rich experience (>15 years) on the construction of versatile macrocyclic compounds, more than 8 representative cyclization methods have been developed Macrocyclic Cpds such as lactam, lactone, sulfonamides, ethers, bi-cyclic & tri-cyclic, etc. can be efficiently synthesized, more than 1500 macrocyclic compounds have been prepared and >30 g of desired products with 20-31 steps have been obtained

>1500 Macrocyclic compounds synthesized
>10 Supported candidates
>30 Grams scaled up 20- 31 steps
15 Years experiences
>8 Represen-tative cyclization methods

Mitsunobu Cyclization

RCM Cyclization

Sulfonamide Formation

Lactam Cyclization

Substitution Cyclization

Click Reaction

Reductive Amination

C-H Activation