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Small Molecule
Small Molecule
WuXi TIDES(Oligonucleotide and Peptide CRDMO Service)
C"R"DMO
C"R"DMO
CR"DM'O
Isotopic Labeling Chemistry
Carbohydrate Chemistry
Nucleoside/tide
Macrocyclic Chemistry
Boron Chemistry
Steroids Chemistry
Nanomedicine
Computer-aided Drug Design
Library
Compound Management
Reaction Condition Screening
Fluorescent Bio-probe and Labeling
Quantum Mechanics
Late Stage Functionalization
Catalysis Screening
Custom Synthesis
Discovery Process Chemistry
Bio-transformation
Impurity Proofing
Isotopic Labeling Chemistry
Crystallization Platform
Analysis & Purification
Fluorine Chemistry
PROTAC <sup>®</sup> Platform
Flow Chemistry Service
Electrochemistry
Photoredox Chemistry
Strong experience in non-radioactive isotopic labeling chemistry with 2H, 13C and 15N
Good combination of WuXi AppTec’s rich chemistry experience with isotope labeling chemistry
Service includes custom synthesis of stable isotope labeled API,small molecule inventory of isotope labeled starting materials and intermediates
Offering radio-active 14C-isotopic labeling service in Shanghai
Accomplished more than 100 stable isotopic labeled projects in the past two years
Stocked 200 labeled chemicals and BBs to support quick delivery
Labeling Design
Route Validation
Labeling Synthesis
Material Release
Isotope selection
Position selection
>=3 (2H /13C / 15N)
Route design
Advanced intermediate
Introduce isotope at the last
Isotope synthesis
Avoid D-H exchange
NMR to identify structure
HRMS for isotope%
HPLC for purity
