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Flow Chemistry Service

Services & Solutions

Services & Solutions

News & Events

Career

Small Molecule

Small Molecule

WuXi TIDES(Oligonucleotide and Peptide CRDMO Service)

C"R"DMO

C"R"DMO

CR"DM'O

Flow Chemistry Service

Carbohydrate Chemistry

Nucleoside/tide

Macrocyclic Chemistry

Boron Chemistry

Steroids Chemistry

Nanomedicine

Computer-aided Drug Design

Library

Compound Management

Reaction Condition Screening

Fluorescent Bio-probe and Labeling

Quantum Mechanics

Late Stage Functionalization

Catalysis Screening

Custom Synthesis

Discovery Process Chemistry

Bio-transformation

Impurity Proofing

Isotopic Labeling Chemistry

Crystallization Platform

Analysis & Purification

Fluorine Chemistry

PROTAC <sup>®</sup> Platform

Flow Chemistry Service

Electrochemistry

Photoredox Chemistry

Flow Chemistry – the better solution for safety/scale up/efficiency

Since 2015, our Flow Chemistry team has provided condition screening and scale-up services for 100+ customers globally.   Our aim is to run in a continuous flow stream  to provide faster, cleaner and safer reactions by integrated synthesis, work-up, and analysis

Flow Chemistry Service Highlights

Easily set up and used for a wide scale from milligram to kilogram

Broad temperature range, from -78 ℃ to 250 ℃

Flow rate range of 0.05 ml/min to 10 ml/min

Up to 4 independently controlled reagent pumps

Quick turnaround time for condition screening, within 2 days

Full experience in milligram to kilogram scale production

More than 10 different continuous reaction systems including Corning and Vapourtec flow reactors

Reaction Types

O3

Nitration

Photo reactions

Metallation reactions

Stability issue reactions

High temperature reactions

High risk reaction: NaN3/BH3/H2O2

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Instruments

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Vapourtec flow system R series

Flexible, precise and automatable

Best in class performance

Idea for med chem and process research

Easy to set up and use

Versatile and robust pumps

Wide range of reaction conditions possible

Cited in over 600 peer reviewed publications

A proven design with over 400 installations worldwide

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Corning flow system

1~5 kg production per day

Outstanding mixing and heat exchange

Low internal volume

High residence time

High chemical durability

Flow rate range of 5 ml/min to 50 ml/min

Broad temperature range, from -60 to 200 ℃

Pressure up to 1.8 Mpa

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Oushisheng flow hydrogenation system

2-5 kg production per day;

Broad temperature range, from r.t. to 200 ℃

Catalyst diameter, from 0.2-2 mm

Flow rate range of 5 ml/min to 50 ml/min

Pressure up to 10 MPa

Flow Chemistry Service from Condition Screening to Scale Up

Condition Screening

Flow Chemistry Development

Flow Chemistry Scale up

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Photo reactor

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Vapourtec flow reactor

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365-850 nm LED flow reactor